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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T27998 | MDK-4204 | Anticancer AgentI,MDK 4204,Anticancer Agent I,MDK4204,Anticancer Agent-I | |
MDK-4204, an anticancer agent, shows significant anti-cancer activity with IC50 values of 8.8 µM and 9.5 µM in PC-3 and DU-145 cells, respectively. | |||
T7309 | TAS-103 dihydrochloride | TAS-103 (dihydrochloride),BMS-247615 dihydrochloride | Topoisomerase |
TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II. | |||
T2830 | Betulinic acid | ALS-357,Lupatic acid,Betulic acid | Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy |
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert... | |||
T61286 | Glyoxalase I inhibitor 7 | ||
Glyoxalase I inhibitor 7 (Compound 6) is a potent inhibitor of glyoxalase I (Glo-I) with an IC50 of 3.65 μM. It exhibits potential as an anticancer agent [1]. | |||
T61103 | Glyoxalase I inhibitor 5 | ||
Glyoxalase I inhibitor 5 (Compound 9h) is a potent inhibitor of glyoxalase I (Glo-I), with an IC50 value of 1.28 μM. This compound holds promise as an anticancer agent [1]. | |||
T61692 | Glyoxalase I inhibitor 6 | ||
Glyoxalase I inhibitor 6 (Compound 9j) is an inhibitor of glyoxalase I (Glo-I) with an IC50 value of 1.13 μM. This compound shows potential as an anticancer agent, demonstrating low toxicity [1]. | |||
T38474 | CL2-MMT-SN38 | CL2-MMT-SN38 | |
CL2-MMT-SN38 is a derivative of SN-38, which is a potent anticancer agent and the active metabolite of Irinotecan (CPT-11), a Topoisomerase I inhibitor. | |||
T79557 | Fac-[Re(CO)3(L6)(H2O)][NO3] | Apoptosis | |
Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function. It exhibits cytotoxicity against prostate cancer cells with an IC50 of 5... | |||
T79558 | Fac-[Re(CO)3(L3)(H2O)][NO3] | ||
Fac-[Re(CO)3(L3)(H2O)][NO3] (Compound 3), a rhenium(I) tricarbonyl aqua complex, acts as an anticancer agent through the induction of mitochondrial dysfunction. It exhibits cytotoxicity against prostate cancer cells, dem... | |||
T83898 | S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine | SFN-Cys,D,L-Sulforaphane-L-cysteine | |
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) is an isothiocyanate derivative, functioning as an active metabolite of sulforaphane, a class I and II histone deacetylase (HDAC) inhibitor, and anticancer agen... |